Across TCGA cell cohorts, SRARP RNA expression is significantly associated with the go_rna of many other GO terms, with 1,527 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SRARP-associated GO terms across cancer lineages are Alpha-beta T cell activation, Cellular response to type II interferon, and Cellular response to corticotropin-releasing hormone stimulus. Each is linked with SRARP in more than 4 cancer types. Because this analysis shows association rather than direction, both SRARP-to-partner and partner-to-SRARP results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRARP→partner) and Y-score (partner→SRARP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Alpha-beta T cell activation →	-0.145	-1.718	<.001	<.001	3	5
BREAST	Cellular response to type II interferon →	-0.131	-2.238	<.001	<.001	3	4
BREAST	Cellular response to corticotropin-releasing hormone stimulus →	+0.864	+1.711	<.001	<.001	3	4
BREAST	Transforming growth factor beta production →	-0.189	-1.581	<.001	.002	3	4
BREAST	Nucleotide-sugar biosynthetic process →	+0.066	+2.321	<.001	.001	3	4
OESOPHAGUS	Positive regulation of protein K48-linked ubiquitination →	-0.128	-0.006	.001	.004	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,527 associations by consensus.

Exploration

SRARP survival (RNA) · tumor vs normal (RNA) · all SRARP data types