Across TCGA patient cohorts, SRA1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,308 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SRA1-associated genes across cancer lineages are ZNF780B, ZNF56, and ZNF528-AS1. Each is linked with SRA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SRA1-to-partner and partner-to-SRA1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRA1→partner) and Y-score (partner→SRA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZNF780B →	-0.755	-0.295	<.001	<.001	3	6
GBM	ZNF56 →	-0.510	-0.214	<.001	<.001	3	6
HNSC	ZNF528-AS1 →	-0.510	-0.221	.007	<.001	3	6
HNSC	UQCRQ →	+0.711	+0.211	<.001	.005	3	6
CCRCC	ZNF704 →	-0.997	-0.279	<.001	<.001	3	5
HNSC	TRMT10B →	-0.704	-0.310	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,308 associations by consensus.

Exploration

SRA1 survival (RNA) · tumor vs normal (RNA) · all SRA1 data types