SQOR

Across TCGA patient cohorts, SQOR protein abundance is significantly associated with the RNA expression of many other genes, with 18,589 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SQOR-associated genes across cancer lineages are ANKRD22, B2M, and PSMB10. Each is linked with SQOR in more than 6 cancer types. Because this analysis shows association rather than direction, both SQOR-to-partner and partner-to-SQOR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SQOR versus ANKRD22 in UCEC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SQOR→partner) and Y-score (partner→SQOR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ANKRD22 →	+1.183	+0.515	<.001	<.001	3	7
GBM	B2M →	+0.831	+0.701	<.001	<.001	3	7
OV	PSMB10 →	+0.989	+0.677	<.001	.001	3	7
HNSC	BRMS1L →	-0.643	-0.523	.001	<.001	3	6
LSCC	SCML2 →	-1.127	-0.463	<.001	<.001	3	6
BRCA	PLAAT4 →	+1.231	+0.365	.002	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,589 associations by consensus.

SQOR vs ANKRD22 — UCEC

Explore this scatter interactively →