SPTSSA

Across TCGA patient cohorts, SPTSSA mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPTSSA-associated genes across cancer lineages are CD8+ Tcm, CD8+ Tem, and Erythrocytes. Each is linked with SPTSSA in more than 1 cancer types. Because this analysis shows association rather than direction, both SPTSSA-to-partner and partner-to-SPTSSA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tcm grouped by SPTSSA-low versus SPTSSA-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPTSSA→partner) and Y-score (partner→SPTSSA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ Tcm →	+0.020	+2.350	.041	.031	3	2
UCEC	CD8+ Tem →	+0.003	+4.606	<.001	.044	3	1
UCEC	Erythrocytes →	+0.031	+3.010	.012	.019	3	1
UCEC	Endothelial cells →	-0.039	-2.279	.040	.036	1	1
UCEC	lymphatic Endothelial cells →	-0.027	-3.405	.025	.005	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CD8+ Tcm by SPTSSA expression — UCEC

Explore this box plot interactively →