SPTSSA

Across TCGA cell cohorts, SPTSSA RNA expression is significantly associated with the go_rna of many other GO terms, with 3,584 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SPTSSA-associated GO terms across cancer lineages are Negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, Monoubiquitinated protein deubiquitination, and Alcohol biosynthetic process. Each is linked with SPTSSA in more than 8 cancer types. Because this analysis shows association rather than direction, both SPTSSA-to-partner and partner-to-SPTSSA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay grouped by SPTSSA-low versus SPTSSA-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPTSSA→partner) and Y-score (partner→SPTSSA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.078	+0.610	.003	.006	3	9
STOMACH	Monoubiquitinated protein deubiquitination →	+0.110	+0.941	.007	.005	3	8
LUNG_SCLC	Alcohol biosynthetic process →	+0.076	+0.909	.004	<.001	3	7
BONE	Negative regulation of transmembrane transport →	+0.126	+1.156	<.001	<.001	3	7
LUNG_NSCLC_LUAD	Tricarboxylic acid metabolic process →	+0.114	+0.937	.002	.001	3	6
SKIN	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition →	+0.083	+0.531	.002	.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,584 associations by consensus.

Negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay by SPTSSA expression — OVARY

Explore this box plot interactively →