SPTLC1P3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SPTLC1P3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,552 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPTLC1P3-associated GO terms across cancer lineages are Modulation by host of symbiont process, Protein modification by small protein removal, and Carbohydrate biosynthetic process. Each is linked with SPTLC1P3 in more than 6 cancer types. Because this analysis shows association rather than direction, both SPTLC1P3-to-partner and partner-to-SPTLC1P3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPTLC1P3→partner) and Y-score (partner→SPTLC1P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECModulation by host of symbiont process →+0.045+0.050<.001.00337
UCECProtein modification by small protein removal →+0.053+0.030<.001.00336
STADCarbohydrate biosynthetic process →+0.039+0.129<.001<.00136
PRADRibosome-associated ubiquitin-dependent protein catabolic process →+0.067+0.025<.001<.00136
STADProtein polyubiquitination →+0.044+0.078<.001.00236
STADNegative regulation of proteasomal ubiquitin-dependent protein catabolic process →+0.051+0.123<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,552 associations by consensus.

Exploration