SPTLC1P1

Across TCGA patient cohorts, SPTLC1P1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,513 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SPTLC1P1-associated proteins across cancer lineages are ZEB1, PPM1F, and CAMSAP2. Each is linked with SPTLC1P1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SPTLC1P1-to-partner and partner-to-SPTLC1P1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPTLC1P1 versus ZEB1 in GBM, with a Pearson correlation of 0.77.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPTLC1P1→partner) and Y-score (partner→SPTLC1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZEB1 →	+0.598	+0.845	<.001	<.001	3	7
UCEC	PPM1F →	+0.305	+0.622	<.001	<.001	3	6
UCEC	CAMSAP2 →	+0.303	+0.745	.002	.001	3	6
LSCC	PRRX1 →	+0.452	+0.704	<.001	.001	3	5
UCEC	QKI →	+0.259	+0.628	<.001	<.001	3	5
UCEC	RAI14 →	+0.394	+0.793	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,513 associations by consensus.

SPTLC1P1 vs ZEB1 — GBM

Explore this scatter interactively →