SPTBN4

Across TCGA patient cohorts, SPTBN4 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,885 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SPTBN4-associated proteins across cancer lineages are CASKIN1_S787, EEF1A2, and FBLL1. Each is linked with SPTBN4 in more than 3 cancer types. Because this analysis shows association rather than direction, both SPTBN4-to-partner and partner-to-SPTBN4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPTBN4 versus CASKIN1_S787 in LSCC, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPTBN4→partner) and Y-score (partner→SPTBN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CASKIN1_S787 →	+1.787	+0.577	<.001	.001	3	4
LSCC	EEF1A2 →	+1.276	+0.347	<.001	<.001	3	4
PDAC	FBLL1 →	+0.762	+0.473	<.001	<.001	3	4
BRCA	SYP →	+1.498	+0.920	<.001	<.001	3	4
LSCC	PALM_S116 →	+0.656	+0.200	.005	.004	3	4
GBM	STXBP1 →	+0.513	+0.422	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,885 associations by consensus.

SPTBN4 vs CASKIN1_S787 — LSCC

Explore this scatter interactively →