SPTBN4

Across TCGA cell cohorts, SPTBN4 protein abundance is significantly associated with the RNA expression of many other genes, with 2,424 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SPTBN4-associated genes across cancer lineages are AARS1, TYMS, and UBE2T. Each is linked with SPTBN4 in more than 5 cancer types. Because this analysis shows association rather than direction, both SPTBN4-to-partner and partner-to-SPTBN4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPTBN4 versus AARS1 in BREAST, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPTBN4→partner) and Y-score (partner→SPTBN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	AARS1 →	-1.038	-0.783	<.001	.002	2	6
BLOOD_Leukemia	TYMS →	-0.605	-0.811	.003	<.001	3	5
BLOOD_Leukemia	UBE2T →	-0.639	-0.575	.003	.005	3	5
BLOOD_Leukemia	E2F2 →	-1.600	-0.983	<.001	<.001	3	5
CNS	MDP1 →	-0.777	-0.693	.001	.001	3	4
BLOOD_Lymphoma	GINS2 →	-1.541	-0.775	.005	.003	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,424 associations by consensus.

SPTBN4 vs AARS1 — BREAST

Explore this scatter interactively →