SPTBN2

Across TCGA patient cohorts, SPTBN2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,782 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SPTBN2-associated genes across cancer lineages are RN7SL12P, NFATC2, and CD48. Each is linked with SPTBN2 in more than 7 cancer types. Because this analysis shows association rather than direction, both SPTBN2-to-partner and partner-to-SPTBN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPTBN2 versus RN7SL12P in UCEC, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPTBN2→partner) and Y-score (partner→SPTBN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL12P →	+1.127	+0.549	<.001	<.001	3	8
LSCC	NFATC2 →	-0.782	-0.608	<.001	<.001	3	6
UCEC	CD48 →	-0.811	-0.438	.001	.002	3	6
HNSC	GRHL1 →	+1.260	+0.692	<.001	<.001	3	6
HNSC	C11orf80 →	+0.819	+0.685	<.001	<.001	3	6
UCEC	TRAV23DV6 →	-1.044	-0.522	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,782 associations by consensus.

SPTBN2 vs RN7SL12P — UCEC

Explore this scatter interactively →