SPTBN1

Across TCGA cell cohorts, SPTBN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,431 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SPTBN1-associated GO terms across cancer lineages are Central nervous system morphogenesis, Response to epidermal growth factor, and Macroautophagy. Each is linked with SPTBN1 in more than 19 cancer types. Because this analysis shows association rather than direction, both SPTBN1-to-partner and partner-to-SPTBN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Central nervous system morphogenesis grouped by SPTBN1-low versus SPTBN1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPTBN1→partner) and Y-score (partner→SPTBN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Central nervous system morphogenesis →	+1.002	+3.540	<.001	<.001	3	20
BONE	Response to epidermal growth factor →	+0.099	+1.240	.002	.005	3	14
SKIN	Macroautophagy →	+0.045	+1.031	.001	<.001	3	14
LUNG_NSCLC_LUAD	Regulation of Golgi inheritance →	+0.114	+0.757	<.001	.001	3	13
SKIN	Phosphatidylinositol biosynthetic process →	+0.062	+0.852	<.001	.003	3	12
PANCREAS	Regulation of cell size →	+0.090	+1.070	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,431 associations by consensus.

Central nervous system morphogenesis by SPTBN1 expression — BLOOD_Lymphoma

Explore this box plot interactively →