Across TCGA patient cohorts, SPTAN1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,302 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SPTAN1-associated genes across cancer lineages are FAM13C, SPTBN1, and CAVIN2. Each is linked with SPTAN1 in more than 8 cancer types. Because this analysis shows association rather than direction, both SPTAN1-to-partner and partner-to-SPTAN1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPTAN1→partner) and Y-score (partner→SPTAN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FAM13C →	+0.757	+0.248	.003	<.001	3	9
UCEC	SPTBN1 →	+0.821	+0.356	<.001	<.001	3	8
LUAD	CAVIN2 →	+1.119	+0.273	<.001	<.001	3	8
OV	EFCC1 →	+0.823	+0.292	<.001	<.001	3	7
LUAD	PGM5 →	+1.086	+0.252	<.001	<.001	3	7
LUAD	NOSTRIN →	+0.993	+0.290	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,302 associations by consensus.

Exploration

SPTAN1 survival (RNA) · tumor vs normal (RNA) · all SPTAN1 data types