SPSB3

Across TCGA patient cohorts, SPSB3 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,090 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SPSB3-associated proteins across cancer lineages are NUDT16L1, RBM12B, and ZZEF1_S1464. Each is linked with SPSB3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SPSB3-to-partner and partner-to-SPSB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPSB3 versus NUDT16L1 in OV, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPSB3→partner) and Y-score (partner→SPSB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NUDT16L1 →	+0.345	+0.169	.001	<.001	3	3
OV	RBM12B →	+0.174	+0.183	.005	<.001	3	3
LSCC	ZZEF1_S1464 →	-0.653	-0.085	<.001	.002	3	2
BRCA	OSCP1 →	+0.501	+0.231	<.001	<.001	3	2
BRCA	PHKG2 →	+0.263	+0.210	.006	.002	3	2
BRCA	PJA1_S365 →	-0.453	-0.157	.007	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,090 associations by consensus.

SPSB3 vs NUDT16L1 — OV

Explore this scatter interactively →