SPSB1

Across TCGA patient cohorts, SPSB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,434 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SPSB1-associated proteins across cancer lineages are PALLD, FILIP1L, and FLNA. Each is linked with SPSB1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SPSB1-to-partner and partner-to-SPSB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPSB1 versus PALLD in OV, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPSB1→partner) and Y-score (partner→SPSB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PALLD →	+0.778	+0.783	<.001	<.001	3	8
UCEC	FILIP1L →	+0.603	+0.517	.003	.002	3	8
COAD	FLNA →	+0.585	+0.533	<.001	<.001	3	8
OV	NNMT →	+1.025	+0.869	<.001	<.001	3	7
BRCA	PDLIM7 →	+0.671	+1.113	<.001	<.001	3	7
OV	PRKG1 →	+0.621	+0.757	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,434 associations by consensus.

SPSB1 vs PALLD — OV

Explore this scatter interactively →