SPSB1

Across TCGA cell cohorts, SPSB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,761 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SPSB1-associated GO terms across cancer lineages are Viral process, Negative regulation of protein-containing complex assembly, and Viral life cycle. Each is linked with SPSB1 in more than 14 cancer types. Because this analysis shows association rather than direction, both SPSB1-to-partner and partner-to-SPSB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral process grouped by SPSB1-low versus SPSB1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPSB1→partner) and Y-score (partner→SPSB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Viral process →	+0.112	+1.788	<.001	<.001	3	15
STOMACH	Negative regulation of protein-containing complex assembly →	+0.078	+1.288	<.001	.005	3	15
LIVER	Viral life cycle →	+0.118	+1.823	<.001	<.001	3	14
LIVER	Biological process involved in symbiotic interaction →	+0.145	+1.515	<.001	.004	2	15
LIVER	Symbiont entry into host →	+0.154	+1.769	<.001	<.001	3	14
LIVER	Symbiont entry into host cell →	+0.154	+1.769	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,761 associations by consensus.

Viral process by SPSB1 expression — LIVER

Explore this box plot interactively →