SPRYD7

Across TCGA patient cohorts, SPRYD7 protein abundance is significantly associated with the RNA expression of many other genes, with 9,097 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SPRYD7-associated genes across cancer lineages are ABCD2, SYNE3, and LINC02084. Each is linked with SPRYD7 in more than 4 cancer types. Because this analysis shows association rather than direction, both SPRYD7-to-partner and partner-to-SPRYD7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPRYD7 versus ABCD2 in HNSC, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPRYD7→partner) and Y-score (partner→SPRYD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ABCD2 →	-0.770	-0.279	<.001	<.001	3	5
HNSC	SYNE3 →	-0.750	-0.247	<.001	<.001	3	5
BRCA	LINC02084 →	-0.460	-0.285	.003	.001	3	5
HNSC	LINC02391 →	-0.619	-0.202	<.001	.001	3	5
OV	DNAJC3 →	+0.779	+0.429	<.001	<.001	3	4
BRCA	INTS6 →	+0.398	+0.340	.007	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,097 associations by consensus.

SPRYD7 vs ABCD2 — HNSC

Explore this scatter interactively →