SPRR2D

Across TCGA patient cohorts, SPRR2D protein abundance is significantly associated with the RNA expression of many other genes, with 9,533 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SPRR2D-associated genes across cancer lineages are SFN, NCCRP1, and SERPINB3. Each is linked with SPRR2D in more than 3 cancer types. Because this analysis shows association rather than direction, both SPRR2D-to-partner and partner-to-SPRR2D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPRR2D versus SFN in UCEC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPRR2D→partner) and Y-score (partner→SPRR2D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SFN →	+2.194	+3.379	.001	.002	3	4
PDAC	NCCRP1 →	+1.988	+2.886	<.001	<.001	3	4
PDAC	SERPINB3 →	+3.976	+2.341	.002	.008	3	4
HNSC	SPINK6 →	+2.198	+1.891	<.001	<.001	3	3
UCEC	FABP5P1 →	+0.975	+1.983	.003	.003	3	3
LSCC	CNFN →	+2.252	+1.974	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,533 associations by consensus.

SPRR2D vs SFN — UCEC

Explore this scatter interactively →