SPRR2D

Across TCGA cell cohorts, SPRR2D RNA expression is significantly associated with the go_rna of many other GO terms, with 1,879 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SPRR2D-associated GO terms across cancer lineages are Viral process, L-histidine transport, and Viral life cycle. Each is linked with SPRR2D in more than 8 cancer types. Because this analysis shows association rather than direction, both SPRR2D-to-partner and partner-to-SPRR2D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral process grouped by SPRR2D-low versus SPRR2D-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPRR2D→partner) and Y-score (partner→SPRR2D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Viral process →	+0.064	+1.897	<.001	<.001	3	9
SKIN	L-histidine transport →	+0.116	+2.717	.003	<.001	3	8
LARGE_INTESTINE	Viral life cycle →	+0.077	+2.032	<.001	<.001	3	8
URINARY_TRACT	Regulation of cytokine-mediated signaling pathway →	+0.050	+1.773	<.001	.008	3	8
LARGE_INTESTINE	Regulation of intrinsic apoptotic signaling pathway →	+0.069	+1.838	<.001	<.001	3	7
BREAST	Negative regulation of defense response →	+0.081	+1.058	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,879 associations by consensus.

Viral process by SPRR2D expression — LARGE_INTESTINE

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