SPRR1B

Across TCGA patient cohorts, SPRR1B RNA expression is significantly associated with the protein abundance of many other proteins, with 10,546 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SPRR1B-associated proteins across cancer lineages are SCEL_S68, TRIM29, and TRIM29_S21. Each is linked with SPRR1B in more than 5 cancer types. Because this analysis shows association rather than direction, both SPRR1B-to-partner and partner-to-SPRR1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPRR1B versus SCEL_S68 in BRCA, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPRR1B→partner) and Y-score (partner→SPRR1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SCEL_S68 →	+2.013	+1.138	<.001	.009	3	6
PDAC	TRIM29 →	+1.160	+2.759	<.001	<.001	3	5
PDAC	TRIM29_S21 →	+1.377	+2.611	<.001	<.001	3	5
LSCC	TRIM29_S489 →	+1.726	+3.027	<.001	<.001	3	5
UCEC	S100A2 →	+1.691	+1.820	<.001	<.001	3	5
UCEC	SERPINB5 →	+1.273	+2.231	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,546 associations by consensus.

SPRR1B vs SCEL_S68 — BRCA

Explore this scatter interactively →