SPRR1B

Across TCGA patient cohorts, SPRR1B protein abundance is significantly associated with the protein abundance of many other proteins, with 12,619 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SPRR1B-associated proteins across cancer lineages are SPRR2D_S38, SPRR3, and SCEL_S312. Each is linked with SPRR1B in more than 4 cancer types. Because this analysis shows association rather than direction, both SPRR1B-to-partner and partner-to-SPRR1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPRR1B versus SPRR2D_S38 in LSCC, with a Pearson correlation of 0.76.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPRR1B→partner) and Y-score (partner→SPRR1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPRR2D_S38 →	+2.800	+1.974	<.001	<.001	3	5
UCEC	SPRR3 →	+1.963	+1.378	<.001	<.001	3	5
HNSC	SCEL_S312 →	+1.436	+1.054	<.001	<.001	3	5
LSCC	SPRR1A →	+2.117	+2.022	<.001	<.001	3	5
LUAD	SPRR1A_T11 →	+2.037	+2.731	<.001	<.001	3	5
LSCC	KRT16 →	+1.607	+1.681	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,619 associations by consensus.

SPRR1B vs SPRR2D_S38 — LSCC

Explore this scatter interactively →