SPRR1B

Across TCGA cell cohorts, SPRR1B RNA expression is significantly associated with the RNA expression of many other genes, with 5,790 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SPRR1B-associated genes across cancer lineages are SPRR1A, KRT16, and KRT6A. Each is linked with SPRR1B in more than 12 cancer types. Because this analysis shows association rather than direction, both SPRR1B-to-partner and partner-to-SPRR1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPRR1B versus SPRR1A in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.87.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPRR1B→partner) and Y-score (partner→SPRR1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	SPRR1A →	+4.095	+4.141	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	KRT16 →	+4.078	+3.993	<.001	<.001	3	10
LUNG_NSCLC_LUSC	KRT6A →	+7.252	+4.377	.001	<.001	1	12
URINARY_TRACT	SPRR3 →	+2.816	+2.752	<.001	<.001	3	10
URINARY_TRACT	GJB4 →	+1.838	+2.860	<.001	<.001	3	9
OESOPHAGUS	SPRR2E →	+2.832	+4.991	.003	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,790 associations by consensus.

SPRR1B vs SPRR1A — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →