SPRR1A

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SPRR1A mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SPRR1A-associated genes across cancer lineages are Monocytes. Each is linked with SPRR1A in more than 1 cancer types. Because this analysis shows association rather than direction, both SPRR1A-to-partner and partner-to-SPRR1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocytes grouped by SPRR1A-low versus SPRR1A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPRR1A→partner) and Y-score (partner→SPRR1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMMonocytes →+0.009+4.810<.001.04331
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Monocytes by SPRR1A expression — SKCM

Box plot of Monocytes in SPRR1A-low vs SPRR1A-high samples in SKCM.

Explore this box plot interactively →

Exploration