SPPL3

Across TCGA cell cohorts, SPPL3 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SPPL3-associated genes across cancer lineages are OR2M3. Each is linked with SPPL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPPL3-to-partner and partner-to-SPPL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2M3 grouped by SPPL3-low versus SPPL3-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPPL3→partner) and Y-score (partner→SPPL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR2M3 →	+0.006	+5.169	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

OR2M3 by SPPL3 expression — BREAST

Explore this box plot interactively →