Across TCGA patient cohorts, SPPL2C RNA expression is significantly associated with the go_rna of many other GO terms, with 6,954 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPPL2C-associated GO terms across cancer lineages are Obsolete histone modification, Protein stabilization, and Positive regulation of double-strand break repair. Each is linked with SPPL2C in more than 13 cancer types. Because this analysis shows association rather than direction, both SPPL2C-to-partner and partner-to-SPPL2C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPPL2C→partner) and Y-score (partner→SPPL2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Obsolete histone modification →	+0.064	+0.042	<.001	<.001	3	14
STAD	Protein stabilization →	+0.069	+0.039	<.001	<.001	3	13
STAD	Positive regulation of double-strand break repair →	+0.065	+0.042	<.001	<.001	3	13
STAD	Positive regulation of DNA metabolic process →	+0.067	+0.045	<.001	<.001	3	13
STAD	Positive regulation of transcription elongation by RNA polymerase II →	+0.069	+0.048	<.001	<.001	3	13
STAD	snRNA 3'-end processing →	+0.060	+0.046	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,954 associations by consensus.

Exploration

SPPL2C survival (RNA) · tumor vs normal (RNA) · all SPPL2C data types