Across TCGA cell cohorts, SPPL2C RNA expression is significantly associated with the go_rna of many other GO terms, with 1,026 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SPPL2C-associated GO terms across cancer lineages are DNA replication-dependent chromatin disassembly, Regulation of coagulation, and Negative regulation of transcription initiation-coupled chromatin remodeling. Each is linked with SPPL2C in more than 3 cancer types. Because this analysis shows association rather than direction, both SPPL2C-to-partner and partner-to-SPPL2C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPPL2C→partner) and Y-score (partner→SPPL2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA replication-dependent chromatin disassembly →	+0.154	+0.085	<.001	.001	3	4
BONE	Regulation of coagulation →	-0.198	-0.089	<.001	.009	3	4
BONE	Negative regulation of transcription initiation-coupled chromatin remodeling →	+0.134	+0.099	<.001	.005	3	3
BONE	Synaptic vesicle targeting →	+0.246	+0.085	<.001	.001	3	3
BONE	Regulation of hemostasis →	-0.183	-0.108	<.001	.003	3	3
BONE	Pyruvate transmembrane transport →	-0.135	-0.080	.006	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,026 associations by consensus.

Exploration

SPPL2C survival (RNA) · tumor vs normal (RNA) · all SPPL2C data types