SPPL2B

Across TCGA patient cohorts, SPPL2B RNA expression is significantly associated with the protein abundance of many other proteins, with 14,265 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SPPL2B-associated proteins across cancer lineages are HNRNPM, THOP1, and SAFB. Each is linked with SPPL2B in more than 5 cancer types. Because this analysis shows association rather than direction, both SPPL2B-to-partner and partner-to-SPPL2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPPL2B versus HNRNPM in GBM, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPPL2B→partner) and Y-score (partner→SPPL2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HNRNPM →	+0.208	+0.566	.005	<.001	3	6
OV	THOP1 →	+0.452	+0.927	<.001	.001	3	5
BRCA	SAFB →	+0.227	+0.593	<.001	<.001	3	5
LSCC	KHSRP_S480 →	+0.461	+0.437	<.001	<.001	3	5
LSCC	STRBP →	+0.544	+0.453	<.001	<.001	3	5
UCEC	TBC1D2B →	-0.380	-0.633	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,265 associations by consensus.

SPPL2B vs HNRNPM — GBM

Explore this scatter interactively →