Across TCGA patient cohorts, SPOUT1 RNA expression is significantly associated with the mutation status of many other genes, with 11,794 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPOUT1-associated genes across cancer lineages are TP53, ATRX, and TTN. Each is linked with SPOUT1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SPOUT1-to-partner and partner-to-SPOUT1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPOUT1→partner) and Y-score (partner→SPOUT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	TP53 →	+3.358	+0.788	.003	.001	1	8
UCEC	ATRX →	+1.619	+0.361	<.001	<.001	3	5
UCEC	TTN →	+0.670	+0.250	<.001	<.001	3	4
UCEC	XIRP2 →	+1.451	+0.206	<.001	.001	3	4
UCEC	ZNF804A →	+2.010	+0.428	<.001	<.001	3	4
LUSC	FCGBP →	+2.079	+0.291	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,794 associations by consensus.

Exploration

SPOUT1 survival (RNA) · tumor vs normal (RNA) · all SPOUT1 data types