Across TCGA patient cohorts, SPOUT1 mutation is significantly associated with the RNA expression of many other genes, with 869 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPOUT1-associated genes across cancer lineages are RNA5SP280, MORF4L1P6, and CYP2C61P. Each is linked with SPOUT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPOUT1-to-partner and partner-to-SPOUT1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPOUT1→partner) and Y-score (partner→SPOUT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP280 →	+0.273	+4.984	<.001	.003	3	2
STAD	MORF4L1P6 →	+0.198	+5.274	<.001	.006	3	2
STAD	CYP2C61P →	+0.309	+5.463	<.001	.005	3	2
UCEC	SNORD11B →	+0.494	+2.476	.003	.001	3	1
UCEC	RN7SL719P →	+0.067	+4.475	<.001	.003	3	1
UCEC	LINC01730 →	+0.551	+3.499	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 869 associations by consensus.

Exploration

SPOUT1 survival (RNA) · tumor vs normal (RNA) · all SPOUT1 data types