Across TCGA cell cohorts, SPOUT1 mutation is significantly associated with the RNA expression of many other genes, with 71 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SPOUT1-associated genes across cancer lineages are C12orf40, NISCH, and PRDM7. Each is linked with SPOUT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPOUT1-to-partner and partner-to-SPOUT1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPOUT1→partner) and Y-score (partner→SPOUT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	C12orf40 →	+0.011	+4.029	<.001	.009	3	2
LARGE_INTESTINE	NISCH →	+0.716	+3.067	.007	.009	3	1
LARGE_INTESTINE	PRDM7 →	+0.152	+3.494	.001	.002	3	1
LARGE_INTESTINE	MAP3K10 →	+0.787	+3.067	.001	.009	3	1
LARGE_INTESTINE	NAB1 →	+1.032	+3.064	<.001	.009	3	1
LARGE_INTESTINE	SLCO1C1 →	+0.436	+4.258	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 71 associations by consensus.

Exploration

SPOUT1 survival (RNA) · tumor vs normal (RNA) · all SPOUT1 data types