SPON2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SPON2 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SPON2-associated genes across cancer lineages are Osteoblast. Each is linked with SPON2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPON2-to-partner and partner-to-SPON2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Osteoblast grouped by SPON2-low versus SPON2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPON2→partner) and Y-score (partner→SPON2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADOsteoblast →+0.055+3.231<.001.00531
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Osteoblast by SPON2 expression — LUAD

Box plot of Osteoblast in SPON2-low vs SPON2-high samples in LUAD.

Explore this box plot interactively →

Exploration