Across TCGA patient cohorts, SPOCK3 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,167 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SPOCK3-associated proteins across cancer lineages are CRMP1, LMOD1, and DNM1. Each is linked with SPOCK3 in more than 5 cancer types. Because this analysis shows association rather than direction, both SPOCK3-to-partner and partner-to-SPOCK3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPOCK3→partner) and Y-score (partner→SPOCK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CRMP1 →	+0.660	+2.046	<.001	<.001	3	6
COAD	LMOD1 →	+0.844	+0.125	<.001	.003	3	5
GBM	DNM1 →	+0.929	+2.384	<.001	<.001	3	5
LSCC	MAP1B →	+0.660	+1.009	<.001	<.001	3	5
UCEC	TMEM119 →	+0.603	+0.664	<.001	.004	3	4
UCEC	VCL_S346 →	+0.367	+0.370	<.001	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,167 associations by consensus.

Exploration

SPOCK3 survival (RNA) · tumor vs normal (RNA) · all SPOCK3 data types