Across TCGA cell cohorts, SPOCK3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,344 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SPOCK3-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Regulation of myoblast fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with SPOCK3 in more than 9 cancer types. Because this analysis shows association rather than direction, both SPOCK3-to-partner and partner-to-SPOCK3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPOCK3→partner) and Y-score (partner→SPOCK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Negative regulation of syncytium formation by plasma membrane fusion →	+0.044	+0.244	.005	.009	3	10
BLOOD_Leukemia	Regulation of myoblast fusion →	+0.042	+0.284	.002	.002	3	9
BLOOD_Leukemia	Regulation of syncytium formation by plasma membrane fusion →	+0.044	+0.321	<.001	<.001	3	9
URINARY_TRACT	Positive regulation of mRNA metabolic process →	+0.061	+0.909	.002	.004	3	8
LUNG_NSCLC_LUAD	Positive regulation of mRNA catabolic process →	+0.046	+0.881	<.001	.001	2	9
BLOOD_Leukemia	Negative regulation of myoblast fusion →	+0.044	+0.263	.008	.004	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,344 associations by consensus.

Exploration

SPOCK3 survival (RNA) · tumor vs normal (RNA) · all SPOCK3 data types