SPNS1

Across TCGA patient cohorts, SPNS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,136 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible SPNS1-associated GO terms across cancer lineages are Meiotic cell cycle process, Protein localization to microtubule organizing center, and Vacuole organization. Each is linked with SPNS1 in more than 29 cancer types. Because this analysis shows association rather than direction, both SPNS1-to-partner and partner-to-SPNS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic cell cycle process grouped by SPNS1-low versus SPNS1-high in ACC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPNS1→partner) and Y-score (partner→SPNS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	Meiotic cell cycle process →	+0.042	+0.649	<.001	<.001	3	29
DLBC	Protein localization to microtubule organizing center →	+0.062	+0.609	<.001	<.001	3	29
SCLC	Vacuole organization →	+0.049	+0.585	<.001	<.001	3	29
DLBC	Regulation of protein serine/threonine kinase activity →	+0.042	+0.616	.001	<.001	3	29
UVM	Nucleotide-sugar biosynthetic process →	+0.052	+0.487	<.001	<.001	3	29
DLBC	Organophosphate ester transport →	+0.037	+0.580	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,136 associations by consensus.

Meiotic cell cycle process by SPNS1 expression — ACC

Explore this box plot interactively →