SPINT4

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, SPINT4 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of SPINT4’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where SPINT4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SPINT4 is over-expressed in tumor.

LUAD are the cancer types where SPINT4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SPINT4 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LUADAllAll+0.302.0151view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

SPINT4–LUAD

Tumor-vs-normal expression box plot for SPINT4 RNA in LUAD.

Open the LUAD breakdown →

Exploration