SPINT1

Across TCGA patient cohorts, SPINT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,331 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SPINT1-associated proteins across cancer lineages are ZFYVE19, ZFYVE19_S144, and ST14. Each is linked with SPINT1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SPINT1-to-partner and partner-to-SPINT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPINT1 versus ZFYVE19 in OV, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPINT1→partner) and Y-score (partner→SPINT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZFYVE19 →	+0.495	+1.132	.001	.005	3	8
BRCA	ZFYVE19_S144 →	+0.457	+0.795	<.001	<.001	3	5
GBM	ST14 →	+0.636	+0.629	<.001	<.001	3	5
GBM	STX3 →	+0.461	+0.692	<.001	<.001	3	5
UCEC	SPTBN2 →	+0.530	+0.901	<.001	<.001	3	4
LSCC	TACSTD2 →	+0.487	+0.438	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,331 associations by consensus.

SPINT1 vs ZFYVE19 — OV

Explore this scatter interactively →