SPINK8

Across TCGA cell cohorts, SPINK8 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,230 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SPINK8-associated GO terms across cancer lineages are Liposaccharide metabolic process, Calcium ion regulated lysosome exocytosis, and Regulation of behavioral fear response. Each is linked with SPINK8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPINK8-to-partner and partner-to-SPINK8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Liposaccharide metabolic process grouped by SPINK8-low versus SPINK8-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPINK8→partner) and Y-score (partner→SPINK8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Liposaccharide metabolic process →	+0.035	+0.117	<.001	.007	3	2
BLOOD_Leukemia	Calcium ion regulated lysosome exocytosis →	+0.113	+0.227	.006	.006	3	2
BLOOD_Leukemia	Regulation of behavioral fear response →	-0.729	-0.178	<.001	.005	3	2
BLOOD_Leukemia	Glycolipid metabolic process →	+0.033	+0.117	<.001	.007	3	2
BREAST	Cellular response to transforming growth factor beta stimulus →	-0.054	-1.346	.005	.008	3	2
BLOOD_Leukemia	Negative regulation of monocyte chemotactic protein-1 production →	-0.106	-0.119	.009	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,230 associations by consensus.

Liposaccharide metabolic process by SPINK8 expression — BLOOD_Leukemia

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