SPINK7

Across TCGA patient cohorts, SPINK7 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,852 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SPINK7-associated proteins across cancer lineages are RAB27B, TBC1D17, and ARHGAP32_S682. Each is linked with SPINK7 in more than 4 cancer types. Because this analysis shows association rather than direction, both SPINK7-to-partner and partner-to-SPINK7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPINK7 versus RAB27B in BRCA, with a Pearson correlation of 0.25.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPINK7→partner) and Y-score (partner→SPINK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RAB27B →	+0.567	+0.102	.003	.001	3	5
BRCA	TBC1D17 →	+0.457	+0.149	<.001	<.001	3	5
BRCA	ARHGAP32_S682 →	+1.054	+0.145	.001	<.001	3	4
HNSC	PLCD1 →	+0.343	+1.668	.001	<.001	3	4
UCEC	UACA →	+0.270	+1.198	.007	.006	3	4
LUAD	EIF2S2 →	-0.243	-0.736	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,852 associations by consensus.

SPINK7 vs RAB27B — BRCA

Explore this scatter interactively →