SPINK7

Across TCGA cell cohorts, SPINK7 RNA expression is significantly associated with the go_rna of many other GO terms, with 583 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SPINK7-associated GO terms across cancer lineages are Muscle contraction, Muscle system process, and Nucleic acid catabolic process. Each is linked with SPINK7 in more than 5 cancer types. Because this analysis shows association rather than direction, both SPINK7-to-partner and partner-to-SPINK7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Muscle contraction grouped by SPINK7-low versus SPINK7-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPINK7→partner) and Y-score (partner→SPINK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Muscle contraction →	+0.061	+0.139	<.001	.004	3	5
KIDNEY	Muscle system process →	+0.048	+0.132	.002	.008	2	6
BLOOD_Lymphoma	Nucleic acid catabolic process →	+0.036	+0.059	<.001	.001	3	3
BLOOD_Lymphoma	Polyuridylation-dependent mRNA catabolic process →	+0.057	+0.056	<.001	.002	3	3
BLOOD_Lymphoma	Protein targeting to ER →	+0.068	+0.050	<.001	.007	3	3
BLOOD_Lymphoma	Regulation of nucleocytoplasmic transport →	+0.042	+0.049	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 583 associations by consensus.

Muscle contraction by SPINK7 expression — KIDNEY

Explore this box plot interactively →