SPINK4

Across TCGA patient cohorts, SPINK4 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,055 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SPINK4-associated proteins across cancer lineages are BAG1, TFF3, and ELAPOR1. Each is linked with SPINK4 in more than 3 cancer types. Because this analysis shows association rather than direction, both SPINK4-to-partner and partner-to-SPINK4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPINK4 versus BAG1 in BRCA, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPINK4→partner) and Y-score (partner→SPINK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BAG1 →	+0.659	+1.433	<.001	<.001	3	4
BRCA	TFF3 →	+1.268	+1.074	<.001	<.001	3	4
COAD	ELAPOR1 →	+0.843	+3.454	<.001	<.001	3	4
UCEC	MAP7D1 →	-0.282	-0.990	.002	.001	3	4
UCEC	IGF2BP2 →	-0.845	-0.943	.002	.001	3	3
BRCA	MLPH →	+1.095	+1.090	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,055 associations by consensus.

SPINK4 vs BAG1 — BRCA

Explore this scatter interactively →