SPIN2P1

Across TCGA pan-cancer cohorts, SPIN2P1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated SPIN2P1 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher SPIN2P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SPIN2P1 expression acts as an unfavorable survival marker, although some lineages such as LUSC and BLCA show a favorable association.

STAD, KIRC, and COAD are the cancer types where SPIN2P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Median	II,III,IV	0.446	0.614	<.001	131	view →
KIRC	DFS	Tertile	All	0.512	0.718	<.001	103	view →
COAD	OS	Median	All	0.696	0.873	<.001	79	view →
KIRP	DFS	Tertile	IV	0.030	0.474	<.001	76	view →
UCEC	DFS	Tertile	All	0.773	0.866	.002	52	view →
LUSC	OS	Quartile	II,III,IV	0.878	0.666	.001	43	view →
BLCA	OS	Median	IV	0.691	0.497	.005	27	view →
LUAD	DFS	Tertile	IV	0.365	0.896	.006	25	view →
LGG	DFS	Quartile	All	0.291	0.467	<.001	20	view →
SKCM	DFS	Quartile	All	0.309	0.165	.008	16	view →
ESCA	DFS	Tertile	IV	0.226	0.704	.024	12	view →
DLBC	DFS	Tertile	All	0.524	0.864	.005	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

SPIN2P1–STAD (DFS)

Open the STAD breakdown →