SPHKAP

Across TCGA patient cohorts, SPHKAP RNA expression is significantly associated with the protein abundance of many other proteins, with 9,016 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SPHKAP-associated proteins across cancer lineages are SCG2, ADD3, and INA. Each is linked with SPHKAP in more than 2 cancer types. Because this analysis shows association rather than direction, both SPHKAP-to-partner and partner-to-SPHKAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPHKAP versus SCG2 in GBM, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPHKAP→partner) and Y-score (partner→SPHKAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SCG2 →	+0.949	+1.365	<.001	<.001	3	3
GBM	ADD3 →	+0.462	+1.234	<.001	<.001	3	3
GBM	INA →	+0.645	+0.718	<.001	.004	3	3
GBM	COLGALT1 →	-0.600	-0.904	<.001	<.001	3	3
GBM	STXBP1 →	+0.873	+0.896	<.001	<.001	3	3
BRCA	UCHL1 →	+0.877	+0.492	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,016 associations by consensus.

SPHKAP vs SCG2 — GBM

Explore this scatter interactively →