SPHKAP

Across TCGA cell cohorts, SPHKAP RNA expression is significantly associated with the go_rna of many other GO terms, with 1,068 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SPHKAP-associated GO terms across cancer lineages are Negative regulation of cell cycle process, Monocarboxylic acid transport, and Nuclear export. Each is linked with SPHKAP in more than 2 cancer types. Because this analysis shows association rather than direction, both SPHKAP-to-partner and partner-to-SPHKAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell cycle process grouped by SPHKAP-low versus SPHKAP-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPHKAP→partner) and Y-score (partner→SPHKAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Negative regulation of cell cycle process →	+0.036	+0.008	.001	.003	3	3
SKIN	Monocarboxylic acid transport →	-0.035	-0.007	.008	.008	3	3
SKIN	Nuclear export →	+0.054	+0.007	<.001	.006	3	3
BONE	Regulation of regulatory T cell differentiation →	+0.109	+1.526	<.001	<.001	3	3
BONE	Purine nucleotide biosynthetic process →	+0.063	+1.530	.001	.001	3	3
SKIN	Proteasomal ubiquitin-independent protein catabolic process →	+0.049	+0.010	.004	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,068 associations by consensus.

Negative regulation of cell cycle process by SPHKAP expression — SKIN

Explore this box plot interactively →