Across TCGA patient cohorts, SPEM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,919 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPEM2-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Positive regulation of DNA repair, and Regulation of DNA-templated DNA replication. Each is linked with SPEM2 in more than 16 cancer types. Because this analysis shows association rather than direction, both SPEM2-to-partner and partner-to-SPEM2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPEM2→partner) and Y-score (partner→SPEM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA metabolic process →	+0.052	+0.060	<.001	<.001	3	17
STAD	Positive regulation of DNA repair →	+0.047	+0.057	<.001	<.001	3	17
ESCA	Regulation of DNA-templated DNA replication →	+0.053	+0.068	<.001	.001	3	16
STAD	Sister chromatid segregation →	+0.055	+0.046	<.001	<.001	3	16
STAD	Negative regulation of mitotic cell cycle phase transition →	+0.049	+0.055	<.001	<.001	3	16
ESCA	Regulation of cell cycle G2/M phase transition →	+0.062	+0.110	.001	.001	2	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,919 associations by consensus.

Exploration

SPEM2 survival (RNA) · tumor vs normal (RNA) · all SPEM2 data types