Across TCGA cell cohorts, SPEM2 RNA expression is significantly associated with the RNA expression of many other genes, with 3,734 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SPEM2-associated genes across cancer lineages are SPEM1, SPEM3, and NLGN2. Each is linked with SPEM2 in more than 14 cancer types. Because this analysis shows association rather than direction, both SPEM2-to-partner and partner-to-SPEM2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPEM2→partner) and Y-score (partner→SPEM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	SPEM1 →	+0.384	+0.181	<.001	<.001	3	15
OVARY	SPEM3 →	+0.031	+0.143	<.001	<.001	3	9
STOMACH	NLGN2 →	+2.174	+0.042	<.001	.006	3	9
SOFT_TISSUE	DOK3 →	+1.337	+0.115	<.001	.003	2	6
LUNG_NSCLC_LUAD	ASIC3 →	+1.290	+0.054	<.001	.002	3	4
STOMACH	ZNF771 →	+0.756	+0.059	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,734 associations by consensus.

Exploration

SPEM2 survival (RNA) · tumor vs normal (RNA) · all SPEM2 data types