SPEF1

Across TCGA cell cohorts, SPEF1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SPEF1-associated genes across cancer lineages are AVP. Each is linked with SPEF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPEF1-to-partner and partner-to-SPEF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by SPEF1-low versus SPEF1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPEF1→partner) and Y-score (partner→SPEF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

AVP by SPEF1 expression — BLOOD_Lymphoma

Explore this box plot interactively →