SPECC1P2

Across TCGA patient cohorts, SPECC1P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,257 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SPECC1P2-associated GO terms across cancer lineages are Protein N-linked glycosylation, Positive regulation of double-strand break repair, and rRNA transcription. Each is linked with SPECC1P2 in more than 7 cancer types. Because this analysis shows association rather than direction, both SPECC1P2-to-partner and partner-to-SPECC1P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein N-linked glycosylation grouped by SPECC1P2-low versus SPECC1P2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPECC1P2→partner) and Y-score (partner→SPECC1P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein N-linked glycosylation →	+0.063	+0.082	<.001	<.001	3	8
STAD	Positive regulation of double-strand break repair →	+0.066	+0.115	<.001	.001	2	8
STAD	rRNA transcription →	+0.067	+0.086	<.001	<.001	3	7
STAD	Protein stabilization →	+0.055	+0.118	<.001	.001	3	7
KIRC	Positive regulation of stem cell population maintenance →	+0.059	+0.015	<.001	<.001	3	6
STAD	Negative regulation of mRNA processing →	+0.060	+0.083	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,257 associations by consensus.

Protein N-linked glycosylation by SPECC1P2 expression — STAD

Explore this box plot interactively →