SPDYE5

Across TCGA patient cohorts, SPDYE5 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,044 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SPDYE5-associated proteins across cancer lineages are LSM4, RCSD1_S68, and MEPCE. Each is linked with SPDYE5 in more than 3 cancer types. Because this analysis shows association rather than direction, both SPDYE5-to-partner and partner-to-SPDYE5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPDYE5 versus LSM4 in HNSC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPDYE5→partner) and Y-score (partner→SPDYE5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LSM4 →	+0.367	+0.784	<.001	<.001	3	4
PDAC	RCSD1_S68 →	-0.450	-0.299	<.001	.001	3	4
LSCC	MEPCE →	+0.304	+0.481	.005	<.001	3	3
HNSC	ZKSCAN8_S177 →	+0.402	+0.566	<.001	.001	3	3
GBM	ZMYM3_S192 →	+0.536	+0.520	.006	.001	3	3
PDAC	WRAP53_S491 →	+0.609	+0.251	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,044 associations by consensus.

SPDYE5 vs LSM4 — HNSC

Explore this scatter interactively →