SPDYE2B

Across TCGA patient cohorts, SPDYE2B RNA expression is significantly associated with the go_rna of many other GO terms, with 6,367 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible SPDYE2B-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, Nuclear-transcribed mRNA poly(A) tail shortening, and Positive regulation of chromosome organization. Each is linked with SPDYE2B in more than 24 cancer types. Because this analysis shows association rather than direction, both SPDYE2B-to-partner and partner-to-SPDYE2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay grouped by SPDYE2B-low versus SPDYE2B-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPDYE2B→partner) and Y-score (partner→SPDYE2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.043	+0.161	<.001	<.001	3	25
STAD	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.050	+0.185	<.001	<.001	3	25
STAD	Positive regulation of chromosome organization →	+0.035	+0.165	<.001	<.001	3	24
STAD	RNA-templated DNA biosynthetic process →	+0.036	+0.175	<.001	<.001	3	24
GBM	Protein demethylation →	+0.050	+0.163	<.001	<.001	3	24
STAD	Nuclear-transcribed mRNA catabolic process →	+0.041	+0.181	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,367 associations by consensus.

Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay by SPDYE2B expression — STAD

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