SPDYE2B

Across TCGA cell cohorts, SPDYE2B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,880 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SPDYE2B-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Negative regulation of translational initiation, and Viral translational termination-reinitiation. Each is linked with SPDYE2B in more than 14 cancer types. Because this analysis shows association rather than direction, both SPDYE2B-to-partner and partner-to-SPDYE2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by SPDYE2B-low versus SPDYE2B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPDYE2B→partner) and Y-score (partner→SPDYE2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.225	+0.356	<.001	<.001	3	15
BONE	Negative regulation of translational initiation →	+0.135	+0.470	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.112	+0.440	<.001	.001	3	15
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.218	+0.494	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of translational initiation →	+0.081	+0.335	<.001	.004	3	14
BONE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.168	+0.413	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,880 associations by consensus.

Pre-mRNA catabolic process by SPDYE2B expression — BONE

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