Across TCGA patient cohorts, SPDYE2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,125 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SPDYE2-associated proteins across cancer lineages are MEPCE, DHX9, and RBM39. Each is linked with SPDYE2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SPDYE2-to-partner and partner-to-SPDYE2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPDYE2→partner) and Y-score (partner→SPDYE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MEPCE →	+0.252	+0.462	.003	.007	3	5
HNSC	DHX9 →	+0.203	+0.749	<.001	.001	3	5
LSCC	RBM39 →	+0.209	+0.477	.001	.001	3	4
COAD	NOL9_S487 →	+0.761	+0.505	.001	<.001	3	4
COAD	SF3B3 →	+0.128	+0.405	.003	.003	3	4
HNSC	CPSF7 →	+0.310	+0.852	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,125 associations by consensus.

Exploration

SPDYE2 survival (RNA) · tumor vs normal (RNA) · all SPDYE2 data types